12.11.08

Early symptoms of diabetes - How to detect early symptoms of diabetes

The early symptoms of diabetes which

Diabetes and high blood pressure, coronary heart disease and cancer is a threat to human health of the four major chronic non-communicable diseases. Since the early symptoms of diabetes was not obvious, they can not rise to the attention of patients and delayed treatment. In order to increase people's awareness of diabetes and increase awareness of self-care, where some of the early symptoms of diabetes.

Patients with diabetes showed polyuria, thirst and drink more, the loss of sugar, is easy to eat more hunger, weight loss, and this is often said that the diabetes "a little more than 3" typical symptoms. Serious illness of diabetes because of the large loss of nutrients, expressed as weight loss, muscle weakness, decreased immune function, prone to respiratory, urinary tract and skin infections, and difficult to control, such as the merger of foot ulcers, often long Buyu, And even had to amputation. More harm is to increase the concentration of blood sugar, blood viscosity, a long time to cause the body's major blood vessels and microvascular disease. Diabetic patients with vascular disease of the large main coronary heart disease and cerebrovascular disease, which occurred in myocardial infarction, cerebral infarction and cerebral hemorrhage caused by diabetes patients is the leading cause of death. Microvascular disease of diabetes mellitus are retinopathy and kidney disease and nerve disease, clinical manifestations may appear numb extremities symmetry pain, blurred vision, lower extremity edema, proteinuria, which can cause serious kidney failure and blindness.

What are the symptoms should have suspected it of diabetes?

1 thirsty drinking water, urine, increased frequency of nocturnal.

Easy to eat more than 2 days, or before lunch, before dinner, nervous hunger of hypoglycemia symptoms.

3, weight loss, fatigue with inability.

4, repeated skin infections, sores are easy to boil long.

5 genital itching for women.

6 great fetal (greater than 4000 grams) reproductive history.

7 foot ulcer Buyu long.

8 blurred vision.

9 symmetry hands or feet numb the pain.

10 Obesity, in particular, the merger has high blood pressure and blood lipids of patients.

There are 11 immediate family members suffering from diabetes. A person with any of the above should be further checks. To the hospital for a check urine sugar, urine sugar has prompted more positive diabetes. Determination of the concentration of glucose is the main basis for the diagnosis of diabetes.

For over 40 years of age, family history of diabetes are overweight or obese, with hypertension, even in the absence of the symptoms of diabetes should be every six months to a year to go to the hospital a check blood sugar. Which took place recently coronary heart disease, myocardial infarction, cerebrovascular disease patients also should be checks on blood sugar, so as not to missed diagnosis.

11.11.08

iabetes is a disease

Diabetes is a disease in which the body doesn't produce or properly use insulin. Insulin is a hormone produced in the pancreas, an organ near the stomach. Insulin is needed to turn sugar and other food into energy. When you have diabetes, your body either doesn’t make enough insulin or can’t use its own insulin as well as it should, or both. This causes sugars to build up too high in your blood.

Diabetes mellitus is defined as a fasting blood glucose of 126 milligrams per deciliter (mg/dL) or more. “Pre-diabetes” is a condition in which blood glucose levels are higher than normal but not yet diabetic. People with pre-diabetes are at increased risk for developing type 2 diabetes, heart disease and stroke, and have one of these conditions:

impaired fasting glucose (100 to 125 mg/dL)
impaired glucose tolerance (fasting glucose less than 126 mg/dL and a glucose level between 140 and 199 mg/dL two hours after taking an oral glucose tolerance test)

Diabetes governance prescriptions

1. Small sea mussels get meat, apparently Dunshu, warm clothes several times a day.
2. 20 large river snail, in clean water basin, to drift sand, cement flesh out a small increase in rice wine and a half cups, mixing, and then to water Dunshu, Yin Tang, the 1st day.

Early symptoms of diabetes self-examination

First of all, need to know what the symptoms of diabetes, you can find traces of it.
Some people feel healthy. For example, weight loss, he felt the money Nanmai old thin, eat and drink the body, may be entirely wasted. Actual symptoms of diabetes is about two blocks. I called a few more than 3, more than 3 What does it mean? Known as much urine, eat more, drink more. Than normal or than the original situation more. At the same time, and body weight and physical decline. Weight and physical decline called a few. Is not thin, not thin majority of diabetics. Is the heaviest weight than the decline that time. If you find you are eating more than the original, more water than the original. But the strength of your body weight is not that good. Eating more than the body should be good, your strength and well, a little drop in body weight, tired easily, check! This is actually a lot of people when blood sugar of diabetes has reached the standard.
The second case is that some people fasting hypoglycemia, he is no more thirsty to drink urine and more. However, he is not hungry before eating feel. This is not under the control meal meal. Do not feel hungry for something to eat flustered. Some people say he's riding off, the way things have to get something to eat, or not to home. This is likely to be slow the secretion of insulin. Insulin secretion and slow sync is not a high blood sugar. Low blood sugar instead of high insulin and the cause of this, it is also a symptom.
There are some complications. For example, itching skin, boils easily long, there is a black spot known as the anterior tibial characterization. Touch a piece of black legs. Consumers can not quickly, not Xiaodiao, a, is black. The front legs are black. This is a lot of people who have diabetes do. Then there is a good vision. Close the distance are not clear. It is not for ophthalmic complications. But because of high blood sugar, eyes of the victims, the patients always see clearly. Of course there are some complications, such as cataract, and retinopathy. Also affected the growth and development, child growth and development of diabetes may be affected. These clues do not give up, as long as there is in fact just can not think of diabetes, there is no check is not. Want to check drop of blood will be able to check out, do not delay. Any of the diseases, including AIDS, said that sooner or later one day be able to cure. Diabetes one day be the cure.

Diabetes and emergency first aid

First of all, to judge the patients belong to the common following the accident and what kind of diabetes
1, ketosis and ketoacidosis
(1) mechanism: As the shortage of insulin, the cells can be used to reduce the energy, leading to speed up the decomposition of body fat. Ketone body fat is to break down after the material, normal little content in the blood, hardly a test. When the fat to speed up decomposition, ketones in the blood increased significantly, that is called ketosis. At this time, it will become acidic blood, called ketoacidosis, and severe cases occur in a coma.
(2) performance:
① suffering from a variety of infections in vulnerable or all of a sudden suspension of the treatment of diabetes occurred.
② loss of appetite, abdominal pain, nausea and vomiting.
③ drowsiness, confusion, the better to speed up breathing, bad breath, such as Ping Guowei, the last occurrence in a coma.
④ laboratory examination: high blood sugar, blood ketone body emerged, blood becomes acidic.
2, hypoglycemia, low blood sugar coma
(1) mechanism
① diabetes drug treatment of oral hypoglycemic agents or insulin injection methods. The results are easy to make to lower blood sugar. However, if the improper use, so that blood sugar drop too much, it would cause the occurrence of low blood sugar.
② If the patient due to various reasons, poor appetite, or not eating, diarrhea, vomiting, but usually in accordance with the level of use of hypoglycemic agents or insulin injections, not only出现低血糖reaction, severe cases can cause low blood sugar coma .
(2) to identify hypoglycemia
① flustered, cold sweat, trembling body.
② abnormal fasting or hunger, nausea.
③ lethargy, drowsiness, headache, lack of concentration.
(3) to identify low blood sugar coma
① before the flustered, cold sweat, nausea feeling, gradually sleeping, it should not be called.
② time in the morning, how is also called the ground, her hair cool, we can see a cold sweat, but found no obvious signs of life is not normal.
③ history of diabetes, oral hypoglycemic agents, in recent days do not normally eat, or diarrhea, vomiting, fever, a gradual emergence of consciousness, trance mind, for the development of the coma.
Diabetic coma principles of first aid
In the past history of diabetes, all of a sudden coma, and no other cause, first of all suspected diabetic coma, and coma may be the emergency first-aid principles.
(1) Lateral Horizontal patients with lateral side of the head to keep airway to remove vomit, to prevent the misuse of attracting from suffocation.
(2) careful observation of changes in the condition if it is found to stop breathing, artificial respiration immediately.
(3) the rapid call "120" emergency calls will be promptly taken to hospital for emergency treatment of patients.
Due to diabetes-induced coma, in addition to the reasons for low blood sugar, blood sugar can cause a significant rise hyperosmolar coma, so in a coma was not clear when the reasons for patients not to be fed sugar water, so as not to add to the disease. And unconscious patients to the syrup to feed easily lead to suffocation or choking.
Diabetic coma first-aid points:
① the past history of diabetes, all of a sudden coma, and no other cause, first of all suspected diabetic coma.
② unconscious by the first-aid principles: to maintain airway and prevent aspiration vomit.
③ call "120" first-aid staff, patients will be sent to the hospital, first of all to check blood sugar in order to determine the direction of the treatment of the disease.
④ Do not feed sugar to the patient in a coma in order to avoid choking or suffocation.
Of the above, there are homes of people with diabetes should keep in mind!
Diabetes after the fall of the first-aid measures
1 to be judged in a coma or sudden death. Usual "health" stable condition, or those who suddenly appeared in 1 hour loss of consciousness, the main artery pulse and fall away, can be found in diabetic patients with heart disease. In the course of treatment of diabetes complicated by hypoglycemia easy coma, ketoacidosis, hyperosmolar nonketotic-coma. In a coma before the general fatigue, anorexia, dizziness, fall. Once the sudden death of the patient should immediately implement the CPR, that is, external cardiac massage, artificial respiration, and so on.
2 is to determine transient ischemic attack (TIA) or stroke. TIA is the carotid artery, vertebral artery and the main artery in the brain lesions caused by transient ischemic neurological deficit or. TIA patients suffering from diabetes and stroke risk of non-diabetic patients 2-3 times. Stroke usually dizziness, vertigo, the side of the limb weakness, paralysis, such as dyskinesia. For all of a sudden loss of consciousness or fell to the ground, as far as possible should move, should not cling to the patient and shake Youhan in an attempt to awaken the patient. Could be released slowly to sit flat, at the same time carefully to head toward the side in order to prevent misuse of inhaled vomit trachea have suffocated. First aid at the scene, call 120 as soon as possible.
3 to determine whether the fracture. According to statistics, diabetes in 1 / 3 have osteoporosis, and easily lead to vertebral compression fractures, hip or neck fracture, and so on. After the fracture may appear deformed limbs, do not leave the normal activities of the joint, bone or bone rubbing a sense of fricative, and so on. By those who are suspected fracture to deal with fractures: to be quiet, warm, bleeding, pain, prevent shock; with gauze bandage, and then fixed on the spot; suspected fracture of the spine to keep the wounded body motionless, in particular, should be avoided All activities of the spine, no-one head, the other foot, and other non-action. Been fixed immediately transferred to hospital.

Diabetes physical therapy

Can be physical with the aid of instruments such as physical therapy (health management). Specific methods are as follows
1) into the pancreas, Lei Xia left corresponding to the waist and put a piece paste
2) election match point program: Feishu - Feishu, Pi Yu - Yu stomach, Shenshu - Shenshu, Zusanli - Sanyinjiao

Diabetic condition monitoring

The goal of diabetes treatment is to control blood sugar close to normal as possible so that it in turn to reduce all kinds of diabetes acute and chronic complications and development and improving the quality of life Bingyou Men, and to achieve this goal is a necessary precondition for the good of condition monitoring. In diabetes patients to monitor the condition of life have an important role, it is only through good condition monitoring can adjust your diet and exercise adjustments, changes in the treatment of insulin to provide the correct reference, otherwise, your treatment of diabetes, your insulin dose adjustments, you Diet and exercise adjustments were blind to grope in the dark what is the difference between them? Remind patients: patients must do a good job in monitoring the detailed records.
Each patient should have their blood glucose self-monitoring diary, and to develop a daily record of good habits, blood glucose self-monitoring diary include:
1. Measuring blood sugar, urine sugar HbAlc or the date, time.
2. And the relationship between food, that is, before eating or after a meal.
3. Urine sugar, or glucose.
4. Injection of insulin or oral hypoglycemic agents served the time and type of dose.
5. Any effect on blood sugar of factors, such as food type and quantity of exercise, illness, and so on.
6. Hypoglycemia symptoms appear, and drugs, eating or exercise the relationship between the symptoms of experience, and so on.
Every time I go to the hospital should be good to bring your blood glucose monitoring diary, with the doctor about how to adjust the treatment.
Finally, if there is any health problems, and in a timely manner should contact your doctor or diabetes to answer the Advisory Network.

Diabetic diet secrets of the festival

First, alcohol:
As the alcohol can be brought to the people of the four against diabetes: 1) drinking interfere with the body of sugar, fat and protein metabolism; 2) the promotion of alcohol diabetes acute and chronic complications of development; 3) block drinking hypoglycemic agents break down And the excretion and easy to cause low blood sugar; 4) alcohol damage the pancreas. Therefore, in diabetics best not to drink during the holidays.
Second, in the face of abundant food to eat what? Diabetes election should Shaoyan less oil and light food. Can not be that big Spodiopogon Rouchao food, eating only on the matter, in fact, the vegetable oil less.
Three,
More meat and less to eat, not scientific: Some people think meat is protein, rice is a polysaccharide, more meat will not cause elevated blood sugar, this is not the case, the meat into the body can be transformed into sugar, on the contrary, if every day to eat Less staple food, but will cause hunger and ketosis.
Four,
Quantitative time, not to loose: to live holidays easy to break the law, and the appetite to eat time and more easily change, which inevitably affects the human body "clock" of the law, and, if only to take medicine on time and on time without eating can also lead to low blood sugar .
Fifth, sugar-free cakes, can not eat: the so-called sugar-free cakes, no sugar, the cake is that food is a polysaccharide, will have the same heat, it can not eat.
Sixth, more food, more medicine will not do: during the festive season, that's more food and then eat some of the drugs can increase does not affect blood sugar, which can not be taken!
This is because not only will not take more than the desired effect, although it also increase the side effects!
Seven, snacks volume increase is not: We suggest that diabetics should be Shaoliangduocan, but some patients mistakenly believe that a limited appetite for increased meal together outside of appetite, and resulted in increased blood sugar, especially the snacks such as peanuts, melon seeds, etc. As a snack food snacks, the more desirable!
Pat, how to eat fruit: in the following five cases, do not eat fruit: 1, do not eat too high blood sugar, fasting blood glucose more than 200mg / L; 2, fasting do not eat dinner, only to eat between meals. 3, do not eat high-sugar, dried fruits and more than fresh fruit, and also limit the amount of food; 4, the exchange did not eat, can eat more fruits and exchange of staple food; 5, do not eat monitoring, monitoring of conditions should be eating Monitored before and after the fruit can be better grasped.
Finally, in the hope that the Friends of diabetes during the holidays, keep in mind three words: "5-song set of non-carriage; law to maintain a good life; happy not to overwork."

The diabetes health care

From the statement in front of the pathological analysis of diabetes is extremely low blood gas symptoms, the health-care methods and the majority of diseases, is still the first step back to the first Yangxue in a gas-San Zhao in the first two strokes, that is, by the guts out Zaoshuizaoqi and to enable rapid rise in blood gas.
An increase in blood gas, along with normal human production of energy, will continue to rise in blood sugar, to a certain extent, will start a gradual decline until the return to normal. In the understanding of this process, the rise in blood sugar do not have to care, as long as the rising sense of strength, abnormal physical symptoms are getting better, it means the disease is slowly moving out of the body are also being gradually recovered.
Uremia and health care, gas at up to a certain extent, the body will start early to deal with accumulated disease, the symptoms may be very complicated, time necessary to find the right medicine practitioners to help deal with.
In the event of any disease symptoms, and doctors did not find the right before their own health care the most appropriate method is to conduct a first-San Zhao, nourishing and gas in the third stroke, cardiac massage by. In accordance with this chapter or in a cold, according to different seasons for different meridians of health care. That is, strengthening the liver through the spring of health care, strengthen the heart by the summer, after the fall of strengthening the lung, and kidney by the strengthening of the winter, and so on.
Description:
From clinical experience, it was found that diabetic patients have muscle appears to be less than the average man, at the same time, in custody for a blood gas after the emergence of high blood sugar symptoms after a period of time and then gradually decline.
We have the usual handshake, will be able to easily from the bone with some of the soft palm of identified diabetic patients who consumed the palm of your hand muscles have been lost. These people usually remain in the physical examination when the symptoms of diabetes could not, be nursed back to health after a two or three months before high blood sugar symptoms of diabetes.
After guiding many of our health care of people with diabetes, take good care of oneself in the process, not for their diabetes any special treatment, the patients be nursed back to health for some time, blood gas rose to a certain extent, when the white hair falling gradually, with black hair grow After diabetes symptoms disappear naturally.
From them, we sum up the experience of diabetes occurred in logic, this logic and traditional knowledge of diabetes is totally different, it can be said is a kind of alternative thinking. However, according to this logic not only be able to accurately predict the occurrence of diabetes, in order to be able to develop more accurate methods of health care, real overcome diabetes.

Several diabetes therapeutic porridge

1: Yao Yu Shan March 7: March 7 5 grams, 60 grams of Health yam, 60 grams of japonica rice, butter amount of japonica rice, add water as usual Zhuzhou law. Peeled yam paste for the butter after speculation, so that setting, with key bits, the release mix well with porridge, for breakfast food. : Runfei spleen, Qi solid. Indications: yin and yang deficiency or Yin Deficiency type 2 diabetes. Zhengjianshenpi fatigue, dry mouth Yangan, loss of appetite, Yao Xi languid, easy to knot or alternating diarrhea and constipation, palpitation, or see and spontaneous perspiration, dizziness or tinnitus, or Ma limb pain, or Shiwumohu. Chihen tongue or a fat tongue bleak, white or dry Toi, the clock can not fine Shen.
2: Pueraria lobata flour porridge: Pueraria lobata 30 grams, 50 grams of japonica rice. Pueraria will slice, Water Mill cheng take starch, water and shelter japonica, and with the powder into the casserole Pueraria lobata, 500 ml water, taking slow fire Zhu Zhi thick porridge. : Chufan heat, Shengjinzhike. Of modern Pueraria pharmacological studies have proven to reduce blood sugar, and cardio-cerebral vascular expansion, with moderate blood pressure lowering effect. Indications: yin deficiency type 2 Huo-wang, Zheng Jian drink more than dry mouth, irritability upset, Xingqingjizao, easy to eat more hunger, dry and hard stool, urine mixed color yellow, less mamillata Tianjin, dry yellow tongue coating, and pulse a few slip.
3: Shengde Huang porridge: 150 grams of fresh raw land, apparently washed with gauze Ji Zhi. First with 50 grams of japonica rice, 500 ml water, boiled thick porridge, juice Shengde Huang will join the slow fire Zaizhu a boil, you can eat, one or two a day. : Heat and cooling blood, Yin Sheng Jin. Modern pharmacological research has shown that raw land to enhance myocardial contraction, and diuretic to lower blood sugar. Indications: yin deficiency heat Sheng-diabetes, Zheng Jian polydipsia drink more, eat more easy day, the amount of frequency, stool stem end. Mamillata less Tianjin, Huang moss and dry, slip a few veins.

Diabetic food and recipes

1, fruit categories:
Apple: cool and, sweet, slightly acid and some varieties, make up with heart Qi, Jin-sheng cough, stomach and spleen, Chu Fan, Jieshu, such as the effectiveness of the sober. Apple as a result of the slow absorption of sugar and evenly, so that it can reduce blood sugar, especially after meal blood sugar, diabetics have a good effect.
Pear: cold, sweet, Micro, a cooler of fruit. Zimbabwe has a sheng, Runfei, heat, cold heart, Xiaotan, Reduce Pathogenic Fire, the only heat cough, such as the role of detoxification. Polydipsia attending fever, cough Feire, Tan Duo, hot wind in children, aphonia sore throat, sore red eyes, constipation big knot, a small yellow urine Dengzheng.
Peach: warm peach, sweet and acid. As a result of a rich peach with glucose and fructose, sweet and juicy, with Chun-sheng, Runchang, promoting blood circulation, eliminate the plot, beneficial blood, the color emollients, such as the effectiveness of Yin convergence Khan. Zimbabwe attending constipation, dry bowel injury, closed, Xu Lao cough, blood tumor, sweating deficiency, Dengzheng coronary heart disease. Peach also has a "color-yi, Laofa solution" effectiveness of our predecessors also "be able to eat peaches Advanced Wrinkle Reducer", said. Tixu apply to old age and beauty. Zhiya between the peach tree with plastic Jianchaling Yin Fu Tao, diabetes and high blood pressure rule.
Oranges: The flesh of cool, Weisuan. Zimbabwe has a sheng heat, gas Xiaotan down, and in an appetizer, sober and so on the efficacy of thirst. Jin injury attending fever, body heat sweat, thirsty, cough Tan Chuan, Wan Nadai nausea, thirst Dengzheng drunk.
Grapefruit: cold, sweet and acid. With gas under Xiaotan, Jianweixiaoshi, edema analgesic, Liyan, and other anti-inflammatory efficacy. Main Zhiwei Bing, food is not the plot, chronic cough, asthma Tanduo, Yang Tong throat, fever Dengzheng thirsty. It has been proved: There are anti-inflammatory effects of grapefruit, which is a component Naringin, there is inhibition of virus infection. At the same time, some people believe that fresh grapefruit juice, containing insulin-like elements, to reduce blood sugar to protect the cardiovascular, diabetes, heart disease, high blood pressure in patients with obesity Chang Shi Yi.
Litchi: warm, sweet and acid. With spleen Qi, nourishing Yigan, thirst, educational, speaks, antidotes, such as antidiarrheal effectiveness. Attending Jiuxie deficiency, more than hiccup, uterine bleeding blood deficiency, enuresis in children, scrofula Li, drug boil, varioliform Dengzheng.
Cherry: warm, sweet. Qi has Buxu, spleen and stomach dysfunction, sweating, expelling wind Touzhen, detoxification, skin ulcers in the efficacy of beauty, and so on. Attending iron deficiency anemia, paralysis, numbness in the limbs, rheumatoid arthritis, gout, back pain, frostbite, anemia, Dengzheng burn. As a result of which contain pectin, to increase the secretion of insulin, blood sugar can drop, the role of the treatment of diabetes.
Yangmei: warm, sweet and acid. Zimbabwe has a sheng quench their thirst of Xiaoshi stomach and effectiveness. Attending expectorant, antiemetic, consumer letter, dysentery, cholera Tuxie, gastrointestinal disorders, diabetes Dengzheng.
Diabetes can eat dark chocolate and blueberry.
2, grain cereals:
Wheat: Effects: Wheat and cool, sweet. Yang Xin has soothe the nerves, kidney, stomach intestinal thick, with the exception of hot thirst, Khan convergence, such as the effectiveness of Zhili. Attending diabetes, disturbed mind, do not bother virtual dormancy, Zheng Chong palpitations, hysteria, diarrhea Dengzheng deficiency.
Oats: Paper, also known as oats, brome, wild wheat. Efficacy: temperature of oats, sweet. And with Yiganling spleen, the effectiveness of oxytocin Hua Chang. Tixu after the main treatment of diabetes, Nadai, constipation, difficulty Dengzheng. In addition, antiperspirants, the efficacy of bleeding, or rule Xu Han, sweating, bleeding Dengzheng. Because of its Hua Chang, oxytocin, the fasting pregnant women.
Buckwheat: also known as naked oats, wheat oil, Wumai, buckwheat flowers, wheat 30 cents, jade Michael, sweet buckwheat. Efficacy: of cold buckwheat, sweet. With wet heat, wide-intestinal appetizer, the next consumer product such as the effectiveness of the gas. Attending the first wind pain, gastrointestinal Ji Zhi, bacillary dysentery, diarrhea fever, sore boil erysipelas diabetes, taken off the whitish Dengzheng; external heat can be antidote. As the buckwheat contains red-fluorescent, in particular, to spend more, some people can have food allergies, light (buckwheat disease), such as ear, nose and swelling and inflammation, etc., eye conjunctivitis, pharyngitis, laryngitis, bronchial Go far, it should be cause for concern. Because of cold, fresh dynamic of the cold, the chronic illness, suffering from skin allergies and stomach Cold those fasting.
Millet: for the efficacy of cold, sweet and salty. Qingxudong with fever, fill Xu Sun, and so on the effectiveness of the spleen and stomach health. The main medical treatment, post-natal Tixu, weak stomach, do not think diet, diarrhea and vomiting, dyspepsia in children, dry mouth Dengzheng polydipsia; Yin and still fluid, Yang Shen of the effectiveness of the gas, dry mouth rule Diabetes , Yao Xi puny, only Xie Li, Li urine; external governance can be red hot and Dan, the fire burns, and so on. Millet for basic food, rheumatism, gout, diabetes, high blood acidity can not eat cereal acid, eat millet will not have any discomfort.
Corn: the effectiveness of sexual-ping, Sweet. In tune with the appetizer, customs facilitation water, hypoglycemic, such as lowering efficacy. Attending poor appetite, chronic nephritis edema, urinary tract stones, and ascites Niaoshao, diabetes, hyperlipidemia, edema, jaundice Dengzheng.
Soy: Soy-ping, Sweet. Buxu with heat to facilitate, dehumidification, spleen, middle-wide effectiveness. Huang weak surface charge, the plot stomach heat, edema, a negative urine, rheumatoid Bitong, Dengzheng habitual constipation. Bean "in width under the gas, Lee stool, swelling drug" effect. Can be dressed in uniforms or control high blood pressure, arteriosclerosis, diabetes and other diseases.
Black beans: black beans and flat, sweet. Yin and Kidney with, promoting blood circulation blood, Lee dehumidifier water, expelling wind, and so on the efficacy of detoxification. Diabetes Kidney attending, infertility, deafness, spontaneous perspiration sweating, and all post-natal disease, stroke, weak legs, heads of dark blood deficiency and lower blood, Zhang Man edema, beriberi, jaundice Dengzheng edema. Wind can also rule Bi twin tendons, bone pain.
Pearl barley: of cool, sweet, light. Heat with drainage, water Shen Shi Lei, such as the effectiveness of the spleen to stop diarrhea. Attending beriberi edema, rheumatoid Bitong, the deficiency diarrhea, red urine short, the twin NF acute pulmonary abscess, appendicitis, appendicitis, hot water, Deng Zheng Shilin Diabetes.
Mung bean: cold, sweet. With heat-clearing and detoxifying, diuretic, and so on the effectiveness of heat. I believe that my sore carbuncle attending heat, a variety of edema, water and fire burn, milk carbuncle, Diabetes, Zhasai, polydipsia heat, blood fat and a variety of Deng Zheng poisoning. And the effectiveness of anti-allergy, urticaria, and other governance allergic diseases.
Pea: Sex-ping, Sweet. And with the lower air, water and so on the effectiveness of detoxification profits. Attending poor urine, Zhang Man in the lower abdomen, and no less than post-natal milk, diabetes, athlete's foot, swollen Dengzheng carbuncle.
Cowpea: Sex-ping, Sweet. Spleen with kidney effectiveness. Attending food product, bloating, indigestion in children, belch, diabetes, Dengzheng off. For external use can relieve antidote.
Lentils: Sex-ping, Sweet. Qu Shu has, Huashi, spleen and middle-effectiveness. Shushi attending diseases, diarrhea deficiency, Chibai off, rickets in children Dengzheng plot.
Tofu: of cool, sweet. Has a wide and stomach, Runzao Jin-sheng, heat and so on the efficacy of detoxification. Mu Chi attending, diabetes, constipation, sore, Feiretanduo, Deng Zheng Wei Huo bad breath, and sulfur solution, iodine and alcohol.
Doufu Pi: also known as yuba, tofu clothing, 1000. -Ping, sweet, light. Qingfei Yangwei have the effect. Main Feire cough, fever injury Tianjin, dry stool end Dengzheng Diabetes.
3, aquatic products:
1, herring: Ctenopharyngodon also known as black, green snail, Ctenopharyngodon Green, Ukraine, such as mackerel. Meat-ping, Sweet. Qi has Yangwei, Xingpi, Lee Huashi water, such as expelling wind Chufan effectiveness. Attending weak stomach, eat less fatigue, weakness wet beriberi, boredom, malaria, Dengzheng discredited by a few. Bile herring have Qingrejiedu role.
2, Loach: Sweet-ping. With Buzhong, wet Jiemin, detoxification, and other anti-inflammatory efficacy. "Compendium of Materia Medica", said: "Loach in the warm Qi." Attending heat jaundice, male erectile dysfunction, premature ejaculation, weak Tixu, Diabetes, sweating in children, viral hepatitis, hemorrhoids, boil fingers, scabies and chronic ulcers for a long time Buyu Deng Zheng. This product can fill-ching, who is a virtual available, both are more suitable for liver and gallbladder disease, diabetes, urinary system diseases, the best take good care of oneself, but not be too fresh, too fresh pain in the stomach, liver disease who have a tendency to avoid liver coma Fresh.
3, mussels: cold, sweet and salty. Yin and with the heat, eyesight and so on the efficacy of detoxification. Fanre attending, Diabetes, taken off the uterine bleeding, hemorrhoids fistula, Mu Chi, cough, Weireoue, alcohol poisoning, eczema, kidney deficiency Dengzheng
4, Shell: cold, sweet and salty. With the heat and dampness, detoxification, reducing the effectiveness. Shibuya attending urine pain, swelling and pain Mu Chi, Tan Chuan, nausea, diabetes, jaundice, Shi Du, athlete's foot, swollen boil Deng Zheng.
5, albus: temperature of the meat, sweet. With Buzhong, Qushi, Zhijing expelling wind, strong bones and so on effectiveness. Greed will be attending belly cold, weak, internal bleeding, premature ejaculation impotence, Rectocele, uterine prolapse, Xu Lao cough, diarrhea diabetes, weak bones, Dengzheng otitis media.
6, clams: cold, salty flavor. Runzao with Yin and benefits of water swelling, phlegm, and so on the efficacy of soft Kennedy. Diabetes deficiency, edema uterine bleeding, vaginal discharge, insomnia, acid waist, Niaoshao, Tan Yin, hemorrhoids, swollen lymph nodes, goiter, and other diseases. Because of cold, the body Yang, Cold spleen and stomach, abdominal pain, diarrhea patients should not eat. Not more food, more food there Poxue role.
7, sea cucumber: warm, salty flavor. Kidney has Yijing, Yangxue Runzao, Yang Qiang, Yin and, Tiaojing, child support, such as the effectiveness of the production profits. Attending blood loss, the disease after the weak, suffering from weight loss fatigue, impotence, nocturnal emission, premature ejaculation, the frequency of urine, blood, after all kinds of anemia, and stimulate the secretion of milk, traumatic bleeding, constipation, dry intestines, tuberculosis, neurasthenia Dengzheng.
Sea cucumber contained in a variety of sea cucumber-can inhibit the fungus and some sarcoma; sea cucumber to protection of rectal cancer radiotherapy response.
Sea cucumber chondroitin sulfate contained in the "Advanced Wrinkle Reducer" anti-aging. Sea cucumber extract can also be similar to the structure of the toxin saponin, the stroke of spastic paralysis effective.
As the temperature of sea cucumber, it is not appropriate to eat, especially weak stomach, then Tanduo Chinese people should not eat or deprivation.
8, escargot: meat and cold, sweet. With a diuretic heat, heat to quench their thirst, such as Liver Yin and effectiveness. Attending a negative urine, hot and humid, jaundice, hemorrhoids, Mu Chi, hematochezia, otitis media, nephritis, diabetes Dengzheng. Escargot flesh of cold, non-digestible, fresh off an easy Diarrhea abdominal pain, relief can be used alcohol solution of Radix mill.
4, other products
1. Propolis: Brazil Propolis has a very good prevention and treatment of the effects of diabetes, you can build up their strength, enhance immunity, to confront as a result of diabetes is not easy to heal the wounds caused by ulcers and symptoms.
2. Pumpkin Seed Oil: Germany nutritionist for eight years after a study found that pumpkin seed oil has a unique nutritional and effectiveness: 1. Containing a variety of fatty acids, mainly B-Sitostesin and linoleic acid, and so on, can effectively To deal with the human body fat, cholesterol, prevent atherosclerosis, diabetes, have a good effect.

one can not be sugar diabetes?

This is, relatively speaking, can not sugar diabetes is the daily diet can not eat sugar and glucose, fructose is in fact able to eat, fructose decomposition of insulin do not need the participation of the major components of honey is fructose, honey to eat for diabetes Or some help.

Diabetes Prevention

First, not overeating, regular life, to eat slowly, eat more vegetables, as far as possible not to eat within a short time with glucose, sucrose large amount of food, so as to prevent the rapid rise in blood sugar in a short period of time, The protection of pancreatic function would be helpful, especially family history of diabetes friends must remember!
Second, regular sex life, prevent infectious diseases; do not eat the amount of antibiotics. Some of infection and excessive antibiotics can induce diabetes.
Third, abnormal glucose tolerance or family history of diabetes can be a friend to the maximum extent possible to prevent the occurrence of diabetes: eat three months of each year nicotinamide, Vb1, Vb6, methyl Vb12 (Methycobal) enhance the function of the pancreas; in The replacement to eat half a season when the Vc, Ve, larger doses, can improve their own immunity, the removal of free radicals. (Also two hours of time each year intramuscular injection Vb12, every two weeks, a day, it is the economy!)
Fourth, more exercise, less stay up all night.
Diabetes is a common multiple in our country at present there are about 2000-3000 million people with diabetes. So far the disease is not a cure, but can be a good control of the disease. If the specialist under the guidance of the correct application of the present three types of basic good treatment, including diet, exercise, hypoglycemic drugs, the combination therapy, and for life-long treatment, the vast majority of patients can be as normal people like to live, work , Old age take care of themselves. Patients with diabetes should learn self-care, chronic positively to the prevention of complications, development, and to prevent disability, death, epidemiological data from the point of view, if the control of fasting blood glucose <7.2mmol / L (130mg/dl), postprandial Blood glucose <8.9mmol / L (160mg/dl), glycated hemoglobin <8% were very few complications, the delay is occurring, the development of effective measures. Therefore, patients with diabetes must follow the strict control of high blood sugar, adhere to the principle of standard treatment, is the fundamental guarantee for the treatment of diabetes, can not be biased, letter-social "You Yi" the so-called "package treatment, cure diabetes," fallacy.

What is the diabetic foot?

As a result of diabetic neuropathy, so that the loss of feeling in the feet, and as a result of deformity and vascular disease, ischemic foot so that the local organization will lose its vitality, therefore, vulnerable to serious injury, ulcers, infections and gangrene, and some require amputation final. These pathological changes in the foot, collectively referred to as diabetic foot. In short, the diabetic foot is feeling lost as a result of neuropathy, ischemic and as a result of the combined organization will lose its vitality and foot infections.

Diabetes Disease

1, What is diabetic retinopathy?
Long-term blood sugar in diabetic patients due to increased metabolism in the body, causing systemic microcirculation. Fundus retinal blood vessels easily damaged, that is, the occurrence of diabetic retinopathy (diabetic retinopathy, DR). Diabetic retinopathy is one of the serious complications of diabetes, diabetes is caused by one of the main reasons the blind.
Epidemiological surveys show that about 75% of great importance to the control of blood sugar in diabetic patients, the disease occurred in 15 years diabetic retinopathy. In diabetic patients, diabetic retinopathy occurs, up to 50%.
Diabetes caused damage to the body of the pathology because of high blood sugar damages blood vessels of the small, it makes the retinal capillary endothelial cells and pericytes damaged, resulting in the loss of normal capillary barrier function, leakage, caused by peripheral edema, Hemorrhage, followed by capillary occlusion of the retina caused by ischemia, a lack of blood supply and nutrition, leading to necrosis and angiogenesis growth factor and the release of the result generated new blood vessels, which will cause a large number of retinal hemorrhage with a large number of vitreous hemorrhage, resulting in Proliferative vitreoretinopathy. Older, the longer the course, the higher the incidence of eye. Young people than older patients with greater danger, often bad prognosis. If diabetes can be controlled in time, only a small chance of having an accident at the same time have less damage to the retina, or retinopathy gradually increased bleeding occurred repeatedly, leading to the proliferation of retinal changes, and even retinal detachment, or complicated cataract.
What are diabetic retinopathy performance?
Diabetic retinopathy is caused due to diabetes, with the exception of symptoms in order to drink more, more food, more urine and urine sugar, characterized by elevated blood sugar, and bright red eyes appeared retinal capillary hemangioma, flame-like bleeding, there is gray in the late Exudative, bright red neovascularization, prone to red vitreous hemorrhage as the main features of the fundus change.
Early eye disease does not affect the macular, vision will not be affected, patients with no symptoms, patients sometimes feel vision loss, or have the immediate shadow flying or fluttering. If the development of the disease 3-5 years or poor control of blood sugar, can cause varying degrees of retinal hemorrhage, effusion, edema, blood vessel tumor. Such as macular eye involvement can occur decreased vision, dark eyes, dark vision centers, vision centers and symptoms such as deformation of material. If repeated retinal bleeding into the vitreous, the patient has consciously before fluttering shadow. When the blood vessels, or angiogenesis massive bleeding into the vitreous cavity, will seriously affect vision and even blindness.
Retinopathy urine disease prevention and control should be?
• to control blood sugar in normal or near normal levels, at the same time to control blood pressure 140/90 mmHg in the normal range.
• proper diet, to strengthen the campaign to control blood sugar.
• Early vision screening and eye, early treatment, keep your vision to improve the quality of life.
2, What is diabetic kidney disease?
Diabetic nephropathy (DN) is a common chronic complications of diabetes, diabetes is one of the leading causes of death. Early DN are 30-80% of the patients for the clinical development of Phase DN, this time accompanied by glomerular filtration rate is reduced and eventually into end-stage renal disease, glomerular for patients with type 1 diabetes the leading cause of death, 2 Type 2 diabetes patients with serious coronary artery and cerebrovascular second only to atherosclerosis.
The main treatment:
1, diabetes education.
2, the control diet.
3, Sports.
4, medication.
5, islet transplantation.
Chinese and Western medicine for the treatment of diabetes difference?
Western medicine down the main blood sugar, complications of chronic diabetes treatment is largely ineffective. Western medicine but also in the human body with a lot of side effects of the strong chemical composition, the long-term use of western medicine on the human body, liver, kidney and a serious injury.
Hypoglycemic and taking Western medicine, the use of insulin in diabetic patients can reduce the damage the body's liver and kidneys, tissues, but not everyone is able to use insulin diabetes, diabetes and some people can not use insulin, in particular the high blood insulin The disease can not be used in patients with diabetes. In addition, improper use of insulin, if prone to low blood sugar, insulin must be in accordance with determination in order to function in the proper use of insulin, diabetes and some patients with insulin antibodies, this time with no apparent effects of insulin therapy, so we should pay attention to the insulin antibody Diabetic patients with insulin resistance on the Elimination of treatment, so that the use of insulin in order to achieve a smooth hypoglycemic. More importantly, the use of Western medicine like insulin and took only hypoglycemic effect, not the efficacy of treatment, no significant complications of diabetes treatment.
At present, there are a lot of traditional Chinese medicine in Western medicine hypoglycemic added products, such products even more harm patients, many patients feel after taking some medicine products, the rapid drop in blood sugar under control, we believe that this is a traditional Chinese medicine treatment Good diabetes drug, which they did not know there must be western medicine (hypoglycemic) components, as a result of which Western medicine (hypoglycemic) component dose is unknown, patients often take a double dose, so that not only organs of the organ more dangerous, and Easily lead to low blood sugar, taking a long-term damage in human organs and to accelerate the occurrence of complications of diabetes, development, and more importantly, delayed treatment of diabetic patients with the best time, a delay of the disease, for patients with physical and psychological suffering even greater .
The real traditional Chinese medicine products and has no direct role in the rapid hypoglycemic, but the adjustment organs, slow hypoglycemic effect is Bianzheng a major role in diagnosis and treatment, which is symptomatic treatment, with the addition and subtraction disease, has played the role of the practice, use of Chinese medicine treatment of diabetes can be reached from the conditioning of internal organs to human organs and patients to improve their own immunity. To restore the body's internal organs function, blood sugar naturally fell, while the body of the constitution will have different degrees of improvement and improved so as to fundamentally treatment (not cure) of diabetes patients back to health.

Causes of diabetes

1, with type 1 diabetes-related factors include the following:
Own immune system deficiencies: in patients with type 1 diabetes can be found in the blood of a variety of autoimmune antibodies, such as glutamic acid decarboxylase antibody (GAD antibodies), ICA (ICA antibody). These abnormal antibodies can damage the body's own insulin secretion of insulin B cells, so that it can not be normal insulin secretion.
Genetic factors: the current study was prompted genetic defects of the incidence of type 1 diabetes on the basis that such genetic defects in the performance of the people on the sixth chromosome abnormalities on HLA antigen. The study prompted scientists: I have type 2 diabetes onset familial characteristics - If you are parents with diabetes, people with no family history, you better have that.
Infection may be contributory factors: you may be surprised, many scientists suspect that the virus can also cause type I diabetes. This is because the type I diabetic patients before the onset of a period of time too often infected with the virus, and type I diabetes "epidemic", often appear in the virus after the pandemic. Viruses, such as those caused by mumps and rubella virus can cause polio, as well as the Coxsackie virus family, I can play a role in type 2 diabetes.
Other factors: such as milk, oxygen free radicals, some of the anti-rat, and other drugs, which can cause diabetes, scientists are studying.
2, with type 2 diabetes-related factors
Genetic factors: type 1 diabetes and similar to type 2 diabetes are also characteristics of familial disease. It is very likely that genes and genetic-related. Such genetic characteristics of type 2 diabetes than type 1 diabetes is more obvious. For example: a twin suffering from type 1 diabetes, and the other 40% of the risk of the disease; but if it is Type 2 diabetes, while another 70% of the risk of type 2 diabetes.
Obesity: Type 2 diabetes may be an important factor in obesity. Can cause genetic causes of obesity, the same can also be caused by type 2 diabetes. Center for patients with body-fat excess fat on the abdomen, and fat than those on the buttocks and thighs are more prone to type 2 diabetes.
Age: Age is also a type 2 diabetes risk factors. Half of the patients with type 2 diabetes in more than 55 years after onset. Elderly patients are prone to diabetes and older people vulnerable to overloading.
Modern way of life: eating high-calorie food and reduce the amount of exercise can also cause diabetes, some people believe that this is caused due to obesity. Obesity and type 2 diabetes, like those in the diet and activity have been used to "Westernization" of Asian and Latin American businessmen in the United States and more popular.
3, diabetes and pregnancy-related factors
Hormone: pregnancy when the placenta will have a variety of fetal development for the growth hormone, the hormones for the healthy growth of the fetus is very important, but it can block the mother's insulin in the body and therefore lead to diabetes. The 24th week of pregnancy, 28 of these hormone cycle is a peak period of pregnancy diabetes is often made of the time.
Genetic basis: the occurrence of gestational diabetes in patients with type 2 diabetes in the future risk of a large (but has nothing to do with type 1 diabetes). This is why some people believe that pregnancy caused by diabetes genes with type 2 diabetes caused by the gene may be related to each other.
Obesity: Obesity is not only easily lead to Type 2 diabetes, also can cause gestational diabetes.
Against diabetes
There is no cure diabetes, the main hazard is its complications, particularly chronic complications.
Acute complications
Diabetic patients with infection: a high incidence of the two reinforce each other, we must Virtue. Common infections, including tuberculosis and respiratory infections, urinary tract infections and skin infections.
Diabetic hyperosmolar syndrome: occur in middle-aged and old, half of the non-diabetic history, clinical manifestations, including severe dehydration, sometimes as a result of paralysis, coma, and other clinical manifestations have been misdiagnosed as cerebral vascular accident, the mortality rate as high as 50%.
Lactic acidosis: Patients with more heart, liver, kidney disease history, or shock, infection, lack of oxygen, drinking, taking a large number of hypoglycemic Ling history of non-specific symptoms, a high mortality rate.
Chronic complications
Large blood vessel complications:
(1) and cerebrovascular: prevalence rate than non-diabetic 3 times higher, diabetes is the main cause of premature deaths or disability, plug-and cerebrovascular diseases more common;
(2) Cardiovascular: The rate of disease in patients with non-diabetic higher than 3 times, is the main reason for premature deaths, in patients with diabetes, coronary heart disease more often in order. Clinical features include a high incidence of coronary heart disease and early onset, diabetes female cardiovascular disease incidence increased more evident, painless myocardial infarction, and other clinical manifestations of atypical found, and so on;
(3) lower limb blood vessels: The prevalence rate than non-diabetic 5 times higher, diabetes and lower extremity amputations are caused by vascular disease than non-diabetic patients with more than 10 times, is caused by diabetic patients with physical disability of the main reasons.
Microvascular complications:
(1) kidney: prevalence rate than non-diabetic uremia 17 times higher, diabetes, especially in patients with type 2 diabetes Ⅰ premature deaths, the main reason. Patients may have proteinuria, high blood pressure, swelling, such as performance, advanced renal failure occurred;
(2) eyes: blind than non-diabetic 25 times higher, diabetes is one of the major reasons disablement.
Neurological complications:
(1) sensory nerve: pain, numbness, hypersensitivity;
(2) motor: seen neural paralysis caused by a single motor, can be partial muscle atrophy;
(3) autonomic: unusual sweating, blood pressure and heart rate, urine retention or incontinence, impotence and diarrhea or constipation, and so on.
Epidemiological studies show that
Patients with type 1 diabetes in the first 2 years occurred in diabetic retinopathy accounted for 2%, more than 15 years the incidence of diabetic retinopathy as much as 98%
Patients with type 2 diabetes for 20 years, the use of insulin or use insulin patients with diabetic retinopathy rates were 60% and 84%
Early retinopathy may occur as bleeding, edema, microvascular tumor, such as leaking the background of change, then the late emergence of new blood vessels proliferative lesions, a view that this disease is often irreversible, leading to diabetes is a major cause of blindness. Although good blood glucose control can delay and reduce the development of diabetic retinopathy, but could not prevent the development of diabetic retinopathy.
Diabetes and genetic
Genetic diabetes will it?
Diabetes and genetic factors, if the parents are diabetic patients, children born with diabetes significantly increased the chance. Use of blood glucose test blood sugar value is credible. Blood glucose meter and blood glucose test measured blood glucose values gap is relatively small. With regard to the issue of whether the medication, you can start eating and control about an hour after meals to carry out appropriate amount of physical activity, sport, in order to heat the body to sweat, and adhere to a month. Attention to the monitoring of blood sugar, such as fasting blood glucose in the 7mmol / L over, we need to increase the service hypoglycemic medication.
After decades of research, agreed that diabetes is more than a cause of the syndrome. Because the relatives of diabetes patients in the incidence of diabetes than non-diabetics in the family, so that a genetic tendency to diabetes. Britain Pyke single observation twins diabetes for 20 years, in 1982, he summed up the 200 pairs of monozygotic twins diabetes analysis of the survey. One single-diabetic twins consistency (that is, in two different times after birth, are suffering from diabetes), non-insulin-dependent diabetes for 90.6%, insulin-dependent diabetes mellitus for 54.4 percent, non-insulin-dependent diabetes mellitus genetic tendency Insulin-dependent diabetes mellitus than the more remarkable. Genetic tendency to diabetes, and both parents are diabetic, his son is not the generation of 100% are suffering from diabetes, only 5% have diabetes, if only one parent has diabetes, diabetes-generation opportunity to fewer, and often inter-generational Genetic. Research shows that diabetes is not a single genetic inheritance, but more mutations. And diabetes is not a genetic disease, but susceptibility to diabetes, there must be some environmental factors to the occurrence of diabetes.

psychological treatment for diabetes

Diabetic Treatment: Psychotherapy
Many people think that diabetes treatment is diet, exercise, and medication. In fact, psychological treatment for diabetes control is very important. Optimistic about the emotional stability to maintain the stability of the internal environment of patients, and anxiety give rise to feelings of stress hormones such as epinephrine, norepinephrine, adrenocorticotropic hormone and glucagon secretion, which antagonist of insulin, causing blood sugar up High, so that aggravate their condition. In the right state of mind and attitude of the disease should be correct under the guidance of a doctor, the initiative to play, learn prevention and treatment of diabetes knowledge, through the urine sugar and blood sugar monitoring, and explore the impact of favorable conditions and unfavorable factors, the characteristics of their own condition, Have strong confidence and perseverance, rather than the treatment of serious tension, persistent for a reasonable diet, physical activity, not do any work. The proper use of the drug to make weight, blood sugar, urine sugar, blood sugar, blood lipid at a reasonable level. Infection, surgery, a major burden on the spirit of the time, it is necessary to correctly deal with in a timely manner. In short, through the psychological support, to achieve effective control and prevention and treatment of diabetes.
The second treatment of diabetes: diet treatment
Hunger breeds discontent, not necessarily exercise every day, but had to eat every day. The diet has a direct impact on diabetes, the diet is very important for the treatment of diabetes. Traditional Chinese medicine: Diabetes more alcohol as a result of Hou Wei, spleen and stomach injuries, transport of dereliction of duty, Xiao-chun consumption, Zongyushangyin and replace them with hot fat-deficiency disease. "Huang Di Nei Jing" said: "This is also made by the plump, the person must be vegetarian and she has more fat, fat people are internal heat, Gan who is in full, so the gas to overflow on Diabetes." "Jing Yue Quan Shu" said: "Diabetes, for its Zhaoduan's disease, are cream of the beam Feigan change in labor satyric of injury, disease who are rich, the poor and those who have little." Pointed out that obesity, More affluent life of this disease, which is modern medicine's understanding of the causes of diabetes in line. As a result of high or low blood sugar and insulin secretion into the number and variety of food is closely related to diet and thus is the basis for the treatment of type 2 diabetes, regardless of what type of diabetes, severity of illness or any complications, and what treatment should be For a long time and strict diet control.
In the early 50's before Chinese and foreign treatment are low carbohydrate, high-fat, high-protein diet based. According to the Clinical Practice has proved that such a diet for diabetes patients are not beneficial to insulin function, diabetes and high fat diet will increase the patient's vascular disease, high-protein diet would be caused by diabetes increased the incidence of kidney disease. At present, medical experts are to promote high-carbohydrate, lower proportion of fat, protein intake of the control diet, to improve blood glucose tolerance have a good effect, the specific content of the diet are as follows:
First, quantitative diet from time to time
According to age, sex, occupation, weight [(length -100) × 0.9] estimated that the total daily calories. Men than women required daily calories to about 5%. The different age requirements are also differences in heat, per kilogram of body weight is generally required number of kilocalories of heat for young people> middle-aged> elderly>, the average high of 5% to 10% per kilogram of body weight / day. The different physical energy consumption per day is different. Light manual per kilogram of body weight daily calorie consumption 30 ~ 35kcal; moderate physical consumption per kilogram of body weight per day 35 ~ 40kcal heat; heavy manual per kg body weight per day to be more than 40kcal heat. In general, pregnant women, nursing mothers, malnutrition and wasting disease should be increased as appropriate, reduce it obese patients to maintain normal body weight of about 5%, the condition can often be satisfied with control.
Second, the reasonable adjustment of the ratio of the three major nutrients
Dietary sugar, fat and protein ratio of the three major nutrients, it is necessary and reasonable adjustment. Not only achieve the purpose of treating disease, but also to meet the body's physiological needs. At present, the American Diabetes Association (ADA) claim: Diabetes patients carbohydrate diet should be accounted for 55% of the total calories to 60%; protein intake of total daily calories should not exceed 15%. Per kilogram of body weight per day to 0.8 ~ 1.2g appropriate. The development phase of the young people and pregnant women, nursing mothers or special vocational and other complications of patients can be Zhuojia to about 1.5g; daily intake of total fat no more than 30% of total calories, per kilogram of body weight per day to 0.6 ~ 1g as well, such as obese patients, in particular, have high blood lipids or atherosclerosis, fat intake should be adjusted as the case may be.
Third, restaurants and the calculation of heat calculation
The supply of nutrients are the body's heat 3: protein, fat, carbohydrates. One gram of protein and carbohydrates for energy 4kcal (1kcal = 4.184kj), per gram of fat to heat 9kcal (37.74kj). Diabetes patients, according to its labor intensity will be needed per person per day, the total calories (kcal) in accordance with the 69% carbohydrate, 15% protein, fat accounted for 25% of the allocated in proportion to derive the various components of the energy supply, and then Per gram of fat thermogenesis 9kcal, carbohydrates and grams of protein per kilo thermogenesis 4 conversion of the supply of different nutritional needs of the patient's weight, three meals a day, or four meals. Three meals a day for the distribution of heat Breakfast 1 / 5, lunch and dinner each 2 / 5. Four heat distribution for the breakfast meal 1 / 7, all three of the remaining 2 / 7. For example: a middle weight 60kg manual, the normal size of adult diabetes patients, according to the daily per kilogram of body weight 40kcal heat calculation, the total calories a day for 2400kcal, according to the proportion of the allocation of more than 1440kcal calories from carbohydrates that is, 360kcal to the heat Since the protein, 600kcal from fat. These need to provide heat supply 360g carbohydrates, 90g protein, 66g fat.
We stress the importance of diet to control the heat methods, not asking people with diabetes every day must be mechanically to calculate, but should be in the hands of this method of calculation, from time to time, or a sharp change in body weight when a bit of arithmetic, work out The next phase of the program of diet, deprivation and sweet, greasy food, diet choice but to seek to have the principle of diversity.
Diabetic Treatment of three: the treatment of movement
Movement therapy is based on the function of patients and disease characteristics, the use of physical exercise to prevent disease and enhance the body resistance to help patients overcome the disease, an effective way to recover. Movement to the physical benefits will be listed in the following training on the specific law. In the treatment of diabetes, exercise therapy is an important component of, especially for elderly patients, obese patients is more important. Traditional Chinese Medicine have long recognized the movement of the diabetes patients the importance of the Sui Dynasty, "from the source of waiting," Tang Dynasty "Taiwan Miyao," Diabetes has been documented in sports therapy. Since then, both on family medical history.
To the mid-eighteenth century, a number of well-known medical experts from abroad have begun to advocate with diabetes should be appropriate to do physical activity, and physical activity, diet, insulin injections as a treatment of diabetes three magic weapons. Some diabetic patients with only light physical training and to adhere to the combination of diet that is used to achieve rehabilitation.

10.11.08

TCM diabetes

Chinese medicine to the disease pathogenesis discussed in some detail. That was mainly due to body-deficiency, weak five internal organs, as a result of complex non-food section, fresh off Feigan, emotional disorders, excessive For workers, which led to Shen Yin deficiency, heat Fei Wei; pathogenesis focus for the heat deficiency, And with this deficiency, the standard for heat; extension of disease in the course of time, Yang and Yin Sun, Yin and Yang are false; deficiency dry and hot, burning liquid waste Jin blood viscosity, blood by blood stagnation Shibuya; Yin Sun and Yang, Yang Hanning, can lead to blood in Shenyang.
1. Deficiency led to the body-body-deficiency reasons: ① congenitally deficient: "Part Lingshu five changes," said: "The five internal organs are weak, good disease elimination hate." Is the birth mother due to lack of support. ② acquired excessive wear and tear: If the drug against evil, Yin Chun wear and tear. ③ source of less than: Jin Yin, chemical and biological weapons, such as damage to the organs, not sex fluid, chemical and biological weapons, such as "Taiwan Miyao Diabetes door," said: "Diabetes, its original launch, this is due to kidney deficiency, Each is made from sweet urine. "④ organs imbalance between yin and yang relationship, and eventually caused too much Yin Sun, will Piansheng Yang, Yang Tai-sheng was addressed to" eliminate "such as" medical legal edema gate doors, "said:" Kidney Secretary Kai He, qi is open from Yang, Yang Tai-sheng whole family is not closed, water down compared with extinction. " Partial recuperating the Kidney-Yang Kang, and so Sheng Xiao Wei Re-good day.
2. Catering section is not, body fat over the long-term food ① Pamela Hou Wei, so that the delivery of the spleen injury, Ji Zhi stomach, hot and dry Yun, Jin Shang Yin consumption, but also the stomach so that the heat, add to consumer-good day . "Q-Bielun yin and yang," said: "Second-yang balance of that extinction." Second-yang refers to the stomach and hand-foot Yang-Ming Yang Ming large intestine. Refers to the stomach in the heat of Ji Zhi, Xiao Wei Re-while good day. Hot on the evil smoke in the lungs, so that the injury Feire Jin, polydipsia appear to drink more. Heat large knot is big knot constipation poor. ② Duotan as a result of fat people, Tanzu of heat, wear and tear can Yin Jin, Yin Jin, chemical and biological weapons but also less heat, heat will resume Shangyin. And so the vicious circle of Diabetes occurs.
3. Emotional disorders, depression Ganqi due to the long-term situation is not Shu-chi, Yu Zhi heat, dryness of Shangyin; or fury, leading to liver up to be missing; gas anesthesia machine, but also of dry heat, and Xiao Fei Wei Shuo Yin of Tianjin, Fei Wei led to the heat, and occurred more thirsty to drink, consumer-good day. Heat deficiency in the course of time, is bound to lead to Yin Deficiency. Diabetes patients are only deficiency heat, and see more drinking, more urine, good day. Time not only for a long time, Yang and Yin Sun and the emergence of micro-Yang Qi, sleepy body, such as fatigue, difficulty eating small, thin stool soft, dry mouth does not want to drink, the more nocturnal during the day and anti-small, thin veins can not, short tongue , Moss thin white or light yellow. This is due to the lung, stomach, kidney by the three-Qi Yin, yang and appear to be putting the yin and yang deficiency syndrome.

Diabetes diagnostic criteria

Diabetes diagnosis based on clinical symptoms and blood sugar. The following is the diagnostic criteria in 1999 WHO, IDF announced to be in the same year the Chinese Medical Association Diabetes Association recognition, and so on, and suggested the implementation of China.
The concentration of glucose units: mmol / l cava (whole blood) capillary veins (plasma)
(Diabetes)
Fasting ≥ 6.1 ≥ 6.1 ≥ 7.0
Sugar 2 hours after the service ≥ 10.0 11.1 ≥ 11.1
(Damage tolerance)
Fasting <6.1 <6.1 <7.0
2 hours after the serving of sugar ≥ 6.7 ≥ 7.8 ≥ 7.8
(Fasting blood glucose damage)
Fasting> 5.6 <6.1> 5.6 <6.1 ≥ 6.1 <7.0
Sugar 2 hours after the service <6.7 <7.8 <7.8
The concentration of glucose units: mg / dl vein (whole blood) capillary veins (plasma)
(Diabetes)
Fasting ≥ 110 ≥ 110> 126
Sugar 2 hours after the service ≥ 180 ≥ 200> 200
(Damage tolerance)
Fasting <110 <110 <126
Sugar 2 hours after the service ≥ 120 ≥ 140 ≥ 140
(Fasting blood glucose damage)
Fasting> 100 <110> 100 <110 ≥ 110 <126
Sugar 2 hours after the service <120 <140 <140
[Diagnosis that required a few]
(A) diagnosed with diabetes:
1, with typical symptoms of fasting blood glucose 126mg/dl (7.0 mmol / l) or postprandial blood glucose ≥ 200mg/dl (11.1 mmol / l).
2, there is no typical symptoms, only fasting blood glucose 126mg/dl (7.0 mmol / l) or postprandial blood glucose 200mg/dl (11.1 mmol / l) should like to repeat that it still amounted to more than value, can be diagnosed with diabetes.
3, there is no typical symptoms, only fasting blood glucose 126mg/dl (7.0 mmol / l) or postprandial blood glucose 200mg/dl (11.1 mmol / l) glucose tolerance test 2 hours blood glucose 200mg/dl (11.1mmol / l) can be diagnosed as Diabetes.
(B) can rule out the possibility of diabetes:
1, 2 hour glucose tolerance, such as 140-200 mg / dl (7.8-11.1 mmol / l), to reduce glucose tolerance; such as fasting blood glucose 110-126 mg / dl (6.1-7.0 mmol / l) for the fasting blood glucose Damage is not diagnosed with diabetes.
2, if the postprandial blood glucose <140mg/dl (7.8 mmol / l) and fasting blood glucose <100mg/dl (5.6mmol / l) can rule out diabetes.
[Notes]
1, a serious and obvious symptoms of high blood sugar, blood sugar level over and above the requirements of indicators can be confirmed.
2, in the acute infection, trauma, surgery or other stress situations, although clearly detected high blood sugar, can not be immediately diagnosed with diabetes.
3, who can not be silent in accordance with a diagnosis of blood sugar, must be more than another diagnostic criteria.
4, most of the children's symptoms of severe diabetes, high blood sugar, urine sugar, U-positive, do not need tolerance test a small number of symptoms were not serious, it would take fasting plasma glucose test or oral glucose tolerance test.
"The World Health Organization in 1985 to develop the criteria for diagnosis of diabetes"
In line with one of the following can be diagnosed with diabetes:
1, typical symptoms of diabetes, blood sugar is higher than any time 11.1mmol / L (200mg/dl).
2, Richard fasting blood glucose, two or more higher than 7.8mmol / L (140mg/dl).
3, fasting blood glucose less than 7.8mmol / L, suspected diabetes, do oral glucose tolerance test, sugar served more than 2 hours after glucose 11.1mmol / L. If there are no symptoms of diabetes, and another needed a blood sugar more than 11.1mmol / L. The above-mentioned value of intravenous plasma glucose concentrations of glucose.
"1997 American Diabetes Association's diagnostic criteria for diabetes"
1, there are symptoms of diabetes, blood glucose and arbitrary ≧ 11.1mmol / L.
2, fasting blood glucose ≧ 7.0mmol / L.
3, 2 hour glucose tolerance test ≧ 11.1mmol / L. OGTT still requested the World Health Organization.
Meet the above criteria, one of the patients in the other day to repeat the above checks, if still in line with one of the three criteria that were diagnosed with diabetes.
Other diagnosis
Glucose tolerance test served 2 hours after glucose ≧ 7.8mmol / L, but lower than 11.1 mmol / L for the diagnosis
Glucose tolerance. Fasting blood glucose greater than or equal to 6.1mmol / L, but lower than 7.0mmol / L for the diagnosis of impaired fasting glucose. Suspected of gestational diabetes, 100g use of oral glucose tolerance test for diagnosis. 100g glucose tolerance test according to the results of the National Diabetes Data Group O'Sulivan validation of diagnostic criteria, the diagnostic criteria in Table 1.
Table 1 O'Sullivan diagnostic criteria (intravenous plasma)
Serving time on an empty stomach 100g sugar 1 hour 2 hours 3 hours
Blood glucose (mmol / l) 5.9 10.6 9.2 8.1
Blood sugar (mg / dl) 105 190 165 145
The establishment of the diagnosis of two or more blood sugar, meet or exceed the value of the value of the above
Gestational diabetes to take the World Health Organization in 1985 to develop the criteria for diagnosis of diabetes, is also feasible.
[Common abbreviation]
WHO - World Health Organization IDF - International Diabetes Federation Diabetes Institute of the Chinese Medical Association
OGTT-tolerance test IGT - damage tolerance IFG - fasting blood glucose damage
DM --- diabetes mmol/L-- mmol per liter mg/dl-- mg dl

Classification of Diabetes

Diabetes type 1 diabetes points (type 1 diabetes) and type 2 diabetes (type 2 diabetes) and gestational diabetes (gestational diabetes). One type 1 diabetes occur in young people, their lack of insulin secretion, insulin and must rely on life-sustaining treatment. Type 2 diabetes was particularly prevalent in the 30-year-old in the future, the elderly, their insulin secretion did not even lower on the high side, is the main cause of the body to insulin insensitivity (that is, insulin resistance). Gestational diabetes (gestational diabetes) is derived from cells of insulin resistance, but their insulin resistance is due to women during pregnancy hormone secretion (hormone) caused by. Gestational diabetes usually self-healing after childbirth.
Insulin is the body's secretion of pancreatic β cells in the body of the only hypoglycemic hormone. Insulin resistance refers to the surrounding tissue in the body's sensitivity to insulin, the organization is not sensitive to insulin, peripheral organizations, such as muscle, fat on insulin to promote glucose uptake occurred in the role of the resistance.
The study found the prevalence of insulin resistance in type 2 diabetes, accounting for almost 90%, may be the incidence of type 2 diabetes one of the main factors.
In patients with type 1 diabetes diagnosed within five years there are very few chronic complications occur, on the contrary,
In patients with type 2 diabetes diagnosed before chronic complications. According to statistics, 50% of newly diagnosed patients with type 2 diabetes has been in existence for one or more chronic complications, some patients are found suffering from complications due to diabetes.
As a result, the diabetes drug treatment should focus on the causes of its focus on improving insulin resistance, as well as pancreatic β cell function, we must be able to choose to improve insulin resistance may be used. Some drug is insulin sensitizer, so that the diabetic patients in a timely and effective treatment and fundamental in the prevention of chronic diabetic complications and development.
Insulin sensitizer can increase the body's own insulin sensitivity, to make their own insulin, "Resurrection" and give full play to the role, then this will make the blood sugar can be re-uptake by the body cells and use, so that blood sugar dropped to the long-term stability And comprehensive control of blood glucose The purpose of the human body can make for a long time to enjoy their own secretion of insulin.
tnbxc diabetes treatment must be based on diet control, exercise for the treatment of the premise. Diabetics should avoid sugar and sugar into the food, to reduce the consumption of high fat and high cholesterol food, moderate consumption of high-fiber starch and food to eat Shaosiduocan. Movement of choice should be carried out under the guidance of a doctor, as far as possible to do full-body exercise, including walking and jogging and so on. On this basis, the appropriate application of insulin sensitizer drugs, rather than excessive use of drugs to stimulate insulin secretion, in order to achieve long-term effective control of blood sugar.

What is Diabetes

Diabetes is one of the most common chronic diseases. With the improvement of living standards, the aging of the population, as well as an increase in the incidence of obesity, diabetes and the incidence was on the rise year by year. Diabetes in China, the incidence of 2%, according to statistics, China has been diagnosed with diabetes amounted to 40,000,000 and 1,000,000 at an annual rate of increase.
Diabetes is the interaction of genetic and environmental factors caused the diseases, clinical high blood sugar as the main indicator, the more common symptoms of drink, urine, as well as wasting food, and so on. The absence of effective diabetes treatment, the body can cause more damage to the system. Caused by an absolute or relative insulin secretion as well as the lack of target cells to reduce the sensitivity to insulin, causing protein, fat, water and electrolytes such as a series of metabolic disorder syndrome, one of the main signs of high blood sugar. Typical clinical cases may occur more urine, drink more, eat more, such as the performance of the thin, that is, "a little more than 3" symptoms.

Diabetes origin of the name

Diabetes (diabetes mellitus) is a chronic blood glucose (the sugar) levels increased metabolic disease characterized by the group. The main feature of high blood sugar, diabetes, polyuria, polydipsia, food, weight loss, fatigue.
Diabetes is an ancient disease. 400 BC, China's first medical book, "Huang Di Nei Jing.-Q" and "Lingshu" on record "Diabetes evidence", "Diabetes patients," the name. Han Zhang famous "Golden" Diabetes Part of the "three" symptoms have been recorded. The early years of the Tang Dynasty, China's famous first words Doctors Zhen pointed out that the urine of patients with diabetes is sweet, in the summer and fall, the urine of patients with diabetes sometimes trick the flies.
The world's first confirmed and treatment of diabetes in China in the Tang Dynasty medical doctor, Wang Tao. Wang Tao according to his father suffer from severe thirst, increased amount of drinking, found Boils and more sore, urine fruit flavor, according to Zhen Yan "old article inspection" of his book: Diabetes patients Biansi small piece of sweet cake. He personally to try his father at an early age, is really sweet. Therefore, for the development of the Diabetes Treatment Program, supplemented by dietary adjustments, so that his father brought under control the disease. He has been written into the experience of these "Taiwan Miyao".
"Taiwan Miyao," than the 10th century Arab doctor Avicenna "medical Code" on the diagnosis and treatment of diabetes as early as 200 years. 600 AD after the British doctor William Thomas referred to the patient's urine, "such as its taste like sugar honey." According to research, diabetes in the nobility of ancient emperors for the disease, occur in obesity, and among those who eat rich.

9.11.08

Low-molecular-weight water-soluble chitosan on the impact of blood sugar in diabetic mice

Key words :chitosan; diabetes; blood sugar; mice



[Abstract] Objective To study the water-soluble low-molecular-weight chitosan on blood sugar in diabetic mice and its mechanism. Methods 42 mice were randomly divided into normal control group (10), diabetes control group (8), chitosan low-dose treatment group (8), chitosan dose in the treatment group (8), Shell PG high-dose treatment group (8), respectively saline, 10 g / L (250 mg / kg) of chitosan, 20 g / L (500 mg / kg) of chitosan, 40 g / L (1 000 mg / kg) oral administration of chitosan in a row 28 d, observed changes in blood sugar in mice, and immunohistochemical methods to observe islet β cells. The results of chitosan dose and high dose treatment group to lower blood sugar, and diabetes compared to the control group, there was a significant difference (F = 29.55, q = 5.13,7.03, P <0.01); chitosan high-dose treatment group islet β cells Diabetes compared with the control group increased. Conclusion of water-soluble chitosan has a lower blood sugar in diabetic mice, which may be related to the promotion of islet β cell proliferation-related.



[Key words] chitosan; diabetes; blood sugar; mice



EFFECTS OF LMWS-CHITOSAN ON BLOOD GLUCOSE IN DIABETIC MICE



YAN CHUN-LING, LIU WAN-SHUN, LIU BING



(Department of Pathophysiology, Qingdao University Medical College, Qingdao 266021, China)



[ABSTRACT] ObjectiveTo investigate the effects of LMWS-chitosan on blood glucose in diabetic mice. MethodsThe mice were divided into normal control group (10 mice), diabetic control group (8 mice), low-dose-treated group, medium-dose - treated group and high-dose-treated group. Intragastric administration with normal saline, chitosan in different doses, ie 10 g / L (250 mg / kg), 20 g / L (500 mg / kg), and 40 g / L ( 1 000 mg / kg), were carried out separately for different groups for 28 days. The levels of blood glucose were measured and the changes of pancreatic islet β cells were observed using immunohistochemical method. ResultsThe blood glucose levels in medium-dose and high - dose group declined, the differences were significant as compared with the diabetic control group (F = 29.55; q = 5.13,7.03; P <0.01). The number of pancreatic islet β cell in high-dose group was sig-nificantly higher than that in diabetic control group. ConclusionLMWS-chitosan could reduce the level of blood glucose in dia-betic mice, which may be related to the proliferation of pancreatic islet β cells.



[KEY WORDS] chitosan; diabetes mellitus; blood glucose; mice



Low-molecular-weight water-soluble chitosan is a safe and reliable natural biological activity of polysaccharide, at home and abroad in recent years relating to chitosan for the treatment of diabetes increased for prevention and treatment of diabetes to create a new way. This study was to explore low-molecular-weight water-soluble chitosan on blood sugar in diabetic mice and its possible mechanism for the clinical treatment of diabetes to provide new ideas and theoretical basis.



1 Materials and Methods



1.1 low-molecular-weight materials, water-soluble chitosan (LMWS-chitosan), molecular weight range of 2 000 to 3 200, the group prepared its own; STZ-(STZ), in the purchase of Sigma Corporation; blood glucose meter from Germany Production; mice, body mass (18 ± 2) g, male, purchased in the city of Qingdao Institute for Drug Control; SABC immunohistochemistry kit, purchased in the Wuhan Bo Shide biological Limited.



1.2 Methods



1.2.1 diabetes animal model of group selection and preparation of 50 mice, familiar environment after the purchase of 1 week. First mice were divided into two groups, normal control group (A), 10, 40 diabetic model group. STZ will be soluble in pH of 4.5 to 0.1 mol / L of citric acid - sodium citrate buffer, the match concentration 20 g / L of the solution. Model mice by intraperitoneal injection of STZ for the 200 mg / kg; A group of mice injected with normal saline equivalent to observe the changes in the mice. 72 h after the end of mouse check blood glucose by enzymatic determination of blood glucose test instrument, blood glucose concentrations higher than 11.1 mmol / L model for success in mice. According to the concentration of blood sugar and body mass in diabetic mice a preliminary screening of selected blood sugar and body mass concentration difference between the smaller diabetic mice, and were divided into four groups, namely, diabetes mellitus in the control group (B group), Shell PG low-dose treatment group (C group), chitosan dose in the treatment group (D), chitosan high-dose treatment group (E). B, C, D, E group with normal saline, respectively, 10 g / L (250 mg / kg) of chitosan, 20 g / L (500 mg / kg) of chitosan, 40 g / L (1 000 mg / kg) per day oral administration of chitosan, for 28 d, ig 28 d after the detection of the mice in each group 4 Yanchun Ling, LIU Wan-shun, Liu Bing, and so on. Low-molecular-weight water-soluble chitosan on blood sugar in diabetic mice 353 affect the level of blood sugar and body mass.



1.2.2 Immunohistochemical detection of oral administration after the end of each of the groups of mice were killed, pancreas tail of the pancreas take part fixed, paraffin section, with SABC method showed that islet β cells, were observed.



1.2.3 Statistical analysis to the results of x ± s said that the group used to compare paired t test and analysis of variance.



The results 2



2.1 animal model of 72 h after STZ injection, the mice elevated blood sugar, failed to remove mold in mice 3, 35 mice were successful model, the model mice were significantly higher than normal blood glucose control group (t = 20.87, P <0.01).



2.2 different concentrations of chitosan on the impact of oral blood glucose in mice 28 d after the end of the, B Group 2 mice died, the rest are to survive. Before treatment, B, C, D, E blood sugar mice in each group were not significantly different. After treatment, B, C group were not significantly different (F = 29.55, q = 2.43, P> 0.05); D, E and Group B group the difference was significant (q = 5.13,7.03, P <0.01); C , E between the two groups of comparison, the difference was significant (q = 4.59, P <0.01). Table 1.



Table 1 with different concentrations of chitosan on blood sugar levels in diabetic mice the impact of (slightly)



2.3 immunohistochemistry results of the Group A section of mouse insulin-positive cells more positive response to a product at the cytoplasm, Brown was black; B group of insulin-positive cells significantly reduced, a small amount of residual cells in the immune response than the color of the product Shallow; C group of insulin-positive cells of the immune response and the number of colors with the B group there was no significant difference; D and Group E immunoreactive cells than the B group increased.



3 discussion



Diabetes is a cause and pathogenesis of endocrine not yet clear - metabolic diseases, mainly due to lack of insulin secretion absolute or relative lack of target cells, as well as lower insulin sensitivity on the rise. According to the pathogenesis of diabetes is divided into different type 1 and type 2 [2], the experimental use of intraperitoneal injection of STZ-induced diabetic mice islet β cell damage, the absolute lack of insulin. Clinically, this type of diabetes patients using insulin injections of the main treatment, medication side effects and the incorrectly Yi Zhi Yi long-term resistance, therefore, to find a new, safe and reliable material must be hypoglycemic. Chitosan is a polysaccharide biopolymer, immune regulation, cancer and multiple functions such as blood fat, there is widespread use of Chinese medicine [3,4]. However, chitosan molecular weight of large, can not dissolve in water, its application subject to certain restrictions. Water-soluble chitosan is a certain degree of chemical modification made soluble in water and to maintain its original biological function of the polysaccharide derivatives. In this paper, experimental results show that the application of high-dose and dose of water-soluble chitosan diabetic mice for a period of time after treatment, the mice decreased blood sugar, and low-dose treatment group decreased blood sugar was not obvious, that water-soluble chitosan Has a hypoglycemic effect, and this effect was dose-dependent. Documents have reported that chitosan on alloxan-induced high blood sugar mice have a significant role in lowering blood sugar, but the mechanism is not clear. In order to preliminary explore the chitosan hypoglycemic mechanism of action, this article experimental mice in each group of islet β cells of the immune staining, showed that diabetes control group of mice with normal pancreatic islet β cells in the control group compared to a significant reduction, This proves that the damage is indeed STZ islet β cells, resulting in reduced secretion of insulin caused by hyperglycemia. , High doses of chitosan in the treatment group of mice islet β cells in diabetic than in the control group increased significantly, which we speculate that chitosan may have to promote islet β cell proliferation, and its drop of diabetes in mice Sugar may be relevant.

Potentilla grass on diabetes prevention and treatment Role of the Clinical Research

Diabetes (diabetes mellitus, DM) is a chronic, multiple diseases, with more complications and morbidity have increased year by year trend, with cancer, cardiovascular disease was the same as the three diseases worldwide.

Potentilla grass (Potentilla discolor Bge), also known as chicken abuse, child day lotus root, chicken Lake, feet, and so on grass, the rose family plant Potentilla grass root zone of grass-wide, are distributed all over the country, the Northeast, North China and other regions There are the same for its plant-wide Potentilla grass Potentilla grass used to do. Root with tannin and flavonoids, sweet, bitter, sex-, heat and cooling blood swelling of detoxification work and governance dysentery, malaria, blood, blood Dengzheng [1]. Shao Changping [2], and so on Potentilla grass mixture to observe the treatment of type 2 diabetes Yin Deficiency evidence of efficacy, Potentilla grass mixture from Potentilla grass, Astragalus, Chinese yam, Cortex, Polygonum multiflorum, and other components of the drug. Random group therapy, oral treatment group Potentilla grass mixture and Desha film, in the control group Desha oral tablets. 80 cases of treatment group, 51 cases of male, female 29 cases; the youngest 39 years old, maximum 68-year-old, with an average age of 55.4; history of diabetes 1 to 5 years in 34 cases, 6 to 10 years in 33 cases, 13 cases more than 10 years, with an average course of disease 6.4 years. Control group of 36 cases, 19 cases of men and women in 17 cases; the youngest 38 years old, maximum 67-year-old, with an average age of 54.3; history of diabetes 1 to 5 years in 15 cases, 6 to 10 years in 17 cases, more than 10 years, 4 cases, the average 6.3 years. No two cases of serious liver, kidney, heart, brain diseases and complications of diabetes, and sex, age, illness, disease, the difference was not statistically significant (P> 0.05). Comparable. Laboratory examination: fasting blood glucose and postprandial blood glucose 2h, quantitative urine sugar, total cholesterol (TC), triglycerides (TG), blood, urine and stool routine, liver and kidney function, and so on. The results showed that the treatment group than those in the treatment of various indicators significantly lower, statistically significant, P <0.01. In the control group after treatment fasting blood glucose, postprandial 2h blood glucose, 24h quantitative urine sugar significantly lower than before treatment, statistically significant, P <0.01; TG, TC no significant decrease was not significant, P> 0.05. Potentilla grass mixture treatment of type 2 diabetes Yin Deficiency permit the precise effect, found no obvious side effects. Ying Ma, Shao-Wen Chen [3] Potentilla grass with a certain degree of insulin secretion of 50 cases of type 2 diabetes patients were observed, compared to the changes in blood sugar. The treatment of 50 patients, male 26 cases, 24 cases of female, age 45 ~ 68 (58.0 ± 7.1) years old, the course of 1.5 ~ 14 (7.6 ± 3.6), body mass index (BMI)> 25 to 19 cases, of which the combined light 12 cases of severe hypertension, hyperlipidemia in 20 cases. FBG (11.82 ± 1.35) mmol / L. 40 cases in the control group, 18 cases of men and women in 22 cases, the average age of 46 ~ 69 (58.5 ± 7.1) years old, the course of 2 ~ 15 (7.7 ± 4.1) years, BMI> 25 to 12 cases, of which 9 cases of high blood pressure combined with mild , 5 cases of hyperlipidemia. FBG (11.58 ± 1.30) mmol / L. In the treatment group and control group of age constitute, BMI, FBG, and so there was no significant difference between the two groups comparable. Two groups of patients had regular exercise and strict diet, oral metformin treatment in the control group, treatment group on this basis, at the same time give Potentilla grass 30g / d, on behalf of tea. 30-day course of treatment for 1, 2, after the assessment of treatment efficacy. The overall results of the efficacy of the treatment group was better than the control group, P <0.05. Potentilla grass glucose in the treatment group compared with the control group there was a significant difference (P <0.05).

Wang Zhenqing [4] containing Potentilla grass-ling treatment of 105 cases of diabetes in patients with diabetes, in which men and 55 cases, 50 cases of women; age 30 to 63 years old; course of 6 to 24 years; glucose 12 ~ 26mmol / L, blood levels of insulin ( 7.5 ± 4) mU / L; complicated by diabetes 36 cases of kidney disease, diabetic retinopathy in 11 cases, 4 cases of diabetic foot, diabetic peripheral neuropathy in 19 cases, 3 cases of cerebral infarction, 6 cases of coronary heart disease, high blood lipids in 10 cases, 11 cases of high cholesterol. Every 20 days fasting blood glucose measured using real sugar law; cholesterol, triglycerides, using enzyme method; hemorheology indicators, using enzyme method; every 10 days, 1 Ci Chen urine sugar as measured using conventional Law. The results of 71 cases were cured, accounting for 67.6 percent; effect those 30 cases, accounting for 28.6 percent; effective in 2 cases, accounting for 1.9 percent; ineffective in 2 cases, accounting for 1.9 percent. 98.1 percent efficient. Fasting blood glucose, cholesterol, triglycerides, whole blood viscosity, whole blood viscosity reduction and treatment of earlier P <0.01, than the plasma viscosity, fibrinogen and treatment of earlier P <0.05, both statistically significant.

Kang Chang-ling [5], and so on the 37 cases of type 2 DM with abnormal lipid metabolism Potentilla grass treatment, 20 cases in which men and women in 17 cases, the average age (60.05 ± 11.58) years old, with an average body mass index (BMI) 23.7 ± 2.5. Pre-treatment of other lipid-lowering drugs out of at least a month, which Application of 32 cases of Shuanggua Lei, sulfonylureas and acarbose drug treatment, 5 cases of application of insulin therapy. All objects better control of blood glucose, fasting blood glucose ≤ 6.5mmol / L, postprandial 2h blood glucose ≤ 10.1mmol / L. Potentilla grass with 30g / d, decoction, and after meals of oral morning. Taking medication before and after weeks 4, 8 were taken on an empty stomach for blood glucose, blood lipids, blood rheology testing. Determination of blood lipids, including triglycerides (TG), cholesterol (TC), low density lipoprotein (LDL-C), high density lipoprotein (HDL-C), apolipoprotein A (ApoA), apolipoprotein B (ApoB ), Including blood rheology viscosity of whole blood, plasma viscosity, fibrinogen, hematocrit. Observation period to monitor the treatment of liver and kidney function. Using statistical analysis of both X ± s said that the group used to compare t check. The results of triglycerides, cholesterol, blood viscosity, plasma viscosity, fibrinogen, hematocrit, apolipoprotein B (ApoB) lower than before treatment. One triglycerides, apolipoprotein B, and the viscosity of whole blood before treatment, the difference was significant (P <0.05), cholesterol, plasma viscosity, fibrinogen, compared with the pre-treatment difference was significant (P <0.01).

Kunming Institute of Botany, Chinese Academy of Sciences Laboratory of Chemical Plant [6] Potentilla grass for the first time from the methanol extracts isolated compounds 6, respectively flavonoid glycosides and triterpenes. Chen Keji, and so that [7], flavonoids can affect the function of islet cells, B, the three can be Terpenoids material impact on glucose metabolism.

In recent years, many Chinese and foreign scholars from plants, separation has a variety of pharmacological activities of compounds, including flavonoids on quite a number of great importance to and from the point of view of diabetes and its complications mechanism to explore its main mechanism of action is to remove free Based, anti-lipid peroxidation and non-enzymatic glycation damage; impact of β-cell function; around the promotion of cell, tissue and target organ for the use of sugar; anti-inflammatory, and enhance immune function; inhibiting aldose reductase; microcirculation and so on. Such as quercetin [8 to 10], silymarin [11], hesperidin [12] in the removal of free radicals, anti-lipid peroxidation and correct the fat and protein metabolism has been reported. Quercetin can significantly reduce the STZ diabetic rats serum total cholesterol, triglycerides, the lipid peroxide content, while no effect on blood sugar in normal rats. Organization of the kidney on lipid peroxide (LPO) and advanced glycation end products (AGEs), pentosi ˉ dine and lipid peroxide fluorescent adducted significantly inhibit urinary albumin excretion decreased, GBM Stromal hyperplasia and showed some improvements. Li Fu, etc. [10] reported that quercetin on experimental diabetic rat heart protective effect, may be related to the removal of free radicals, such as cholesterol-lowering biological activity. QU to explore in the treatment of diabetic kidney disease mechanisms, silymarin diabetic rats by inhibiting the aorta and kidney glycation and oxidation of non-control of chronic vascular complications of diabetes and diabetic kidney disease. Hesperidin in inhibiting protease glycosylation, the prevention of diabetes complications and Aminoguanidine has a similar effect. , The flavonoids anti-diabetes and its complications pharmacological research for the role of animal testing stage, clinical trials report only a small number. In recent years, scholars at home and abroad, of natural medicine and traditional Chinese medicine attaches great importance to the study. Flavonoids source of drug development, the new extract the active ingredients and pharmacological effects, so that it expanded the scope of clinical applications, and its mechanism of action and pharmacological research is still the focus of future research. Potentilla grass of flavonoids drug side effects, not only reduces blood sugar, can also enhance the role of heat-clearing and detoxifying the body immune function, prevention and treatment DM complications, and its low price, great value for development. With modern medicine, the rapid development of science and technology, it is necessary to do an in-depth study on its mechanism of action, in order to promote the clinical application of the treatment of diabetes and its complications and new drug research and development and provide a theoretical basis.

8.11.08

Diabetes is a chronic blood glucose levels increased metabolic disease characterized by the group

Diabetes (diabetes mellitus) is a chronic blood glucose (the sugar) levels increased metabolic disease characterized by the group. The main feature of high blood sugar, diabetes, polyuria, polydipsia, food, weight loss, fatigue.
The absence of effective diabetes treatment, the body can cause more damage to the system. Caused by an absolute or relative insulin secretion as well as the lack of target cells to reduce the sensitivity to insulin, causing protein, fat, water and electrolytes such as a series of metabolic disorder syndrome, one of the main signs of high blood sugar. Typical clinical cases may occur more urine, drink more, eat more, such as the performance of the thin, that is, "a little more than 3" symptoms.



Diabetes type 1 diabetes points (type 1 diabetes) and type 2 diabetes (type 2 diabetes) and gestational diabetes (gestational diabetes). One type 1 diabetes occur in young people, their lack of insulin secretion, insulin and must rely on life-sustaining treatment. Type 2 diabetes was particularly prevalent in the 30-year-old in the future, the elderly, their insulin secretion did not even lower on the high side, is the main cause of the body to insulin insensitivity (that is, insulin resistance). Gestational diabetes (gestational diabetes) is derived from cells of insulin resistance, but their insulin resistance is due to women during pregnancy hormone secretion (hormone) caused by. Gestational diabetes usually self-healing after childbirth.


Insulin is the body's secretion of pancreatic β cells in the body of the only hypoglycemic hormone. Insulin resistance refers to the surrounding tissue in the body's sensitivity to insulin, the organization is not sensitive to insulin, peripheral organizations, such as muscle, fat on insulin to promote glucose uptake occurred in the role of the resistance.


The study found the prevalence of insulin resistance in type 2 diabetes, accounting for almost 90%, may be the incidence of type 2 diabetes one of the main factors.


In patients with type 1 diabetes diagnosed within five years there are very few chronic complications occur, on the contrary,


In patients with type 2 diabetes diagnosed before chronic complications. According to statistics, 50% of newly diagnosed patients with type 2 diabetes has been in existence for one or more chronic complications, some patients are found suffering from complications due to diabetes.


As a result, the diabetes drug treatment should focus on the causes of its focus on improving insulin resistance, as well as pancreatic β cell function, we must be able to choose to improve insulin resistance may be used. Some drug is insulin sensitizer, so that the diabetic patients in a timely and effective treatment and fundamental in the prevention of chronic diabetic complications and development.


Insulin sensitizer can increase the body's own insulin sensitivity, to make their own insulin, "Resurrection" and give full play to the role, then this will make the blood sugar can be re-uptake by the body cells and use, so that blood sugar dropped to the long-term stability And comprehensive control of blood glucose The purpose of the human body can make for a long time to enjoy their own secretion of insulin.




tnbxc diabetes treatment must be based on diet control, exercise for the treatment of the premise. Diabetics should avoid sugar and sugar into the food, to reduce the consumption of high fat and high cholesterol food, moderate consumption of high-fiber starch and food to eat Shaosiduocan. Movement of choice should be carried out under the guidance of a doctor, as far as possible to do full-body exercise, including walking and jogging and so on. On this basis, the appropriate application of insulin sensitizer drugs, rather than excessive use of drugs to stimulate insulin secretion, in order to achieve long-term effective control of blood sugar.



Diabetes diagnosis based on clinical symptoms and blood sugar. The following is the diagnostic criteria in 1999 WHO, IDF announced to be in the same year the Chinese Medical Association Diabetes Association recognition, and so on, and suggested the implementation of China.




Diabetes diagnostic criteria:

The concentration of glucose units: mmol / l cava (whole blood) capillary veins (plasma)


(Diabetes)


Fasting ≥ 6.1 ≥ 6.1 ≥ 7.0


Sugar 2 hours after the service ≥ 10.0 11.1 ≥ 11.1


(Damage tolerance)


Fasting <6.1 <6.1 <7.0


2 hours after the serving of sugar ≥ 6.7 ≥ 7.8 ≥ 7.8


(Fasting blood glucose damage)


Fasting> 5.6 <6.1> 5.6 <6.1 ≥ 6.1 <7.0


Sugar 2 hours after the service <6.7 <7.8 <7.8


The concentration of glucose units: mg / dl vein (whole blood) capillary veins (plasma)


(Diabetes)


Fasting ≥ 110 ≥ 110> 126


Sugar 2 hours after the service ≥ 180 ≥ 200> 200


(Damage tolerance)


Fasting <110 <110 <126


Sugar 2 hours after the service ≥ 120 ≥ 140 ≥ 140


(Fasting blood glucose damage)


Fasting> 100 <110> 100 <110 ≥ 110 <126


Sugar 2 hours after the service <120 <140 <140